Fig 1.
Identification of positive and negative LAMP results using blue LED light illumination with a visualization unit that is integral to the Loopamp LF-160 incubator.
Fig 2.
STARD diagram describing the flow of samples from VL suspects in the study.
Table 1.
Clinical and demographic data of patients suspected of VL, distributed as case and controls after lymph node aspirate microscopy, participating in this study.
Table 2.
Sensitivity, specificity, and positive and negative predictive values of the different diagnostic tests compared to lymph node aspirate microscopy (LNA-M), in a group of 185 VL suspects tested by all methods.
Fig 3.
Plots of the false discovery rate and false omission rate with varying prevalence.
Note that for RDT the sensitivity is set to an arbitrary 99.9% and for LAMP-WB QIA specificity set to 99.9% from 100%.
Table 3.
Details and summary of the diagnostic performance of different studies using LAMP for VL diagnosis compared to our study.
Fig 4.
Role of Loopamp Leishmania Detection Kit in the VL diagnostic algorithm.