Table 1.
Studies from which data was extracted for the analysis.
HI: Haemagglutination inhibition, PRNT: Plaque reduction neutralisation titre, ELISA: Enzyme linked immunosorbent assay.
Fig 1.
Estimated probability of apparent disease given infection by study.
Probability densities of estimates for the apparent proportion in primary (i) and secondary (ii) infection for each study (Analysis A for each study separately).
Fig 2.
Overall estimated probability of apparent disease given infection.
(i) Probability densities of estimates of the apparent proportion in primary and secondary infections from cohort studies (Analysis A). (ii) Probability densities of estimates including a period of cross-immunity (Analysis D). (iii) Probability densities of estimates from cluster studies (Analysis C). For (i) and (iii) estimates for primary infection shown in green, secondary infection in orange and for (ii) estimates for primary infection shown in green, secondary infections in the year after infection in brown and secondary infections in the subsequent years in orange.
Fig 3.
Estimated risk of infection from cohort studies.
The yearly probability of infection in the cohort studies for each study year (from Analysis A all studies together).
Fig 4.
Estimated risk of infection from cluster studies.
The probability of infection in the time of follow up for those in the cluster around an index case (Analysis C).
Fig 5.
Estimated probability of apparent disease given infection by serotype.
Probability densities of estimates for the apparent proportion in primary (i) and secondary (ii) infection across serotypes (Analysis B).