Table 1.
Guidelines for the treatment of ordinary scabies.
Fig 1.
Structure of the voltage-gated sodium channel.
The channel consists of 4 homologous domains (domains I to IV), with 6 transmembrane segments each (S1 to S6).
Fig 2.
GST catalyzes the formation of a thioester bond between reduced glutathione and the drug, forming a glutathione S conjugate of the drug. GST, glutathione S-transferase.
Fig 3.
Mechanism of action of ABC transporters.
Upon ATP binding, the transporter changes its configuration to allow the export of the drug to the extracellular space. ABC, ATP-binding cassette.
Fig 4.
Mechanism of action of ivermectin on ligand-gated Cl channels.
Upon drug binding, the pore of the channel opens, allowing Cl to enter the cell. These channels also respond to endogenous ligands such as GABA and glutamate. Cl, chloride.