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Fig 1.

Magnetic resonance imaging (MRI).

Axial non-contrast (fluid-attenuated inversion recovery (FLAIR) MRI.

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Fig 2.

PRISMA chart showing the flow of publications via the review process.

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Table 1.

Characteristics of the included cases.

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Fig 3.

Meta-analysis.

(A) Forest plot of ADEM prevalence among other neurological disorders. Showing the pooled event rate with 95% CI using fixed-effect model. (B) Forest plot of ADEM prevalence within dengue patients. Showing the pooled event rate with 95% CI using a random-effects model. (C) Forest plot of neurological disorders prevalence within dengue patients. Showing the pooled event rate with 95% CI using fixed-effect model.

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Fig 4.

The frequency of each manifestation if included in more than two cases.

(A) dengue-related manifestations, (B) ADEM-related manifestations.

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Table 2.

The main manifestations, treatments used for ADEM and outcomes of the included cases.

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Table 3.

The association of patients’ characteristics and manifestations with ADEM cases’ outcomes.

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Fig 5.

Classification tree models indicating the significant predictors for: partial recovery (A) bad outcomes (B) of ADEM compared with complete recovery.

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