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Fig 1.

Study flow diagram.

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Table 1.

Mean days of symptoms prior to ETU arrival for all patients and for individual subgroups.

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Fig 2.

Kaplan-Meier survival analysis by symptom day for EBOV positive patients.

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Fig 3.

A. Kaplan-Meier survival analysis by day of illness for EBOV positive patients disaggregated by sex. B. Kaplan-Meier survival analysis by day of illness for EBOV positive patients disaggregated by age. *Variables have been abbreviated: Abdominal Pain = “Abd Pain”; Nausea/Vomiting = “Vomiting”; Myalgias/Arthralgias = “Myalgias”; Conjunctivitis = “Red Eyes”.

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Table 2.

Baseline demographics and mortality risk by demographic subgroup for EBOV positive patients with known symptom onset date.

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Fig 4.

A. Signs/Symptoms at triage for all EBOV positive patients (n = 470)*. B. Signs/Symptoms over length of illness for all EBOV positive patients (n = 422). *Variables have been combined: Myalgias/Arthralgias = "Bone Pain", "Bone and Muscle Pain" and "Joint Pain"; Nausea/Vomiting = "Nausea" and "Vomiting"; Dysphagia = "Swallowing Problems" and "Sore Throat"; Conjunctivitis = "Red Injected Eyes" and "Conjunctivitis" Variables have been abbreviated: Abdominal Pain = “Abd Pain”; Nausea/Vomiting = “Vomiting”; Myalgias/Arthralgias = “Myalgias”; Conjunctivitis = “Red Eyes”.

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Fig 5.

(A-D). Symptoms by day of illness for surviving EBOV positive patients (E-H) symptoms by day of illness for non-surviving EBOV positive patients. * Numbers along the x-axis indicate the number of patients providing data for that day. Variables have been abbreviated: Abdominal Pain = “Abd Pain”; Nausea/Vomiting = “Vomiting”; Myalgias/Arthralgias = “Myalgias”; Conjunctivitis = “Red Eyes”.

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Table 3.

Multivariable regression model for mortality based on signs/symptoms present at any time in the first week of illness and signs/symptoms present at any time over the total length of illness*.

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Table 3 Expand

Fig 6.

CT values by day of illness and final outcome for EBOV positive patients.

*Numbers along x-axis indicate the number of patients providing data for that day.

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Table 4.

Initial cycle threshold (CT) values and mean CT values over entire length of illness for all EBOV positive patients and for individual demographic subgroups.

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