Fig 1.
Map of the location of the three Merida suburbs (inset) and distribution of treatment and control blocks within each.
Fig 2.
House positivity (proportion of Ae. aegypti infested houses) by treatment and survey date.
Panel (A) shows positivity for adult Ae. aegypti and panel (B) positivity for bloodfed female Ae. aegypti. Asterisks (*) indicate statistically significant (P<0.05) difference between each treatment and the control, after a mixed-effects logistic regression model (Table 1).
Table 1.
Odds ratios (OR) estimated from a mixed-effects logistic regression model evaluating impact of treatment (deltamethrin vs control and bendiocarb vs control) on each adult entomologic metric.
The model included city block (where individual observations are nested) and cluster (grouping of 3 treatments) as random intercepts. ORs were calculated by considering control blocks (i.e., unsprayed) as comparison. Numbers in bold show statistically significant (P<0.05) difference between the treatment and the control.
Fig 3.
Average (±SE) number of Ae. aegypti collected per survey date and by treatment.
Panel (A) shows positivity for adult Ae. aegypti and panel (B) positivity for bloodfed female Ae. aegypti. Vertical gray line indicates the timing of the intervention. Asterisks (*) indicate statistically significant (P<0.05) difference between each treatment and the control, mixed-effects Poisson regression model (Table 2).
Table 2.
Incidence rate ratios (IRR) estimated from a mixed-effects Poisson regression model evaluating effect of treatment (deltamethrin vs control and bendiocarb vs control) on each adult entomologic metric.
The model included city block (where individual observations are nested) and cluster (grouping of 3 treatments) as random intercepts. IRRs were calculated by considering control blocks as comparison. Numbers in bold show statistically significant (P<0.05) difference between the treatment and the control.
Fig 4.
Results from intensity bottle bioassays evaluating the susceptibility of local Ae. aegypti populations to deltamethrin, defined as knock-down after 30 minutes of exposure to the the diagnostic dose (1x) and at twice, five and ten times the diagnostic dose.
Each letter in the Y axis indicates a locality (SL = San Lorenzo, Itz = Itzincab, ACIM = Acim) and treatment (C = control, B = bendiocarb, D = deltamethrin).
Fig 5.
Cone bioassay data showing average mortality of susceptible Ae. aegypti (New Orleans strain) to both insecticides applied in houses belonging to this study at 1–3 months post intervention.
Error bars indicate 95% CI of the mean value.