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Table 1.

QPCR positivity and negativity based on molecular specific RD1 patterns for each species of MTBC.

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Fig 1.

Study flowchart.

aCT: computerized tomography scan, MRI: magnetic resonance imaging; b Reference standard = MTBC culture + and /or at least two + CRS criteria; cCRS: Composite reference standard: (i) TB clinical symptoms, (ii) histology/cytology findings, (iii) radiological tests, (iv) therapeutic response to anti-TB treatment (ATT). dculture and CRS were negative and patient had improvement without ATT. +: positive.

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Table 2.

Reference standard details for EPTB diagnosis.

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Table 3.

Accuracy of MTBC RD qPCR assay, smear microscopy and culture.

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Table 4.

MTBC species identification by multiplex MTBC-RD qPCR on extrapulmonary specimens in EPTB patients according to the reference standard*.

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Table 5.

Comparison of the qPCR results to the other conventional methodsa for MTBC species identification.

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