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Fig 1.

Map of the state of Rio de Janeiro showing georeferenced PCM cases from this study according to health access and urban-rural distribution.

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Table 1.

Demographic, clinical, and prognostic profile in 29 acute juvenile PCM patients.

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Table 2.

Serological and therapeutic results in 29 acute juvenile PCM patients.

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Table 3.

Clinical specimens from which PCM was diagnosed.

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Fig 2.

Lymph node and skin involvement in 2 patients from the present study.

(A) Cervical lymph node enlargement with a “bull’s neck” appearance in a female patient. (B) The same patient after 35 months of amphotericin B, itraconazole, and sulfamethoxazole/trimethoprim treatment. (C) Extensive ulcerative skin lesions on the face of a male patient. (D) The same patient after 48 months of sulfamethoxazole/trimethoprim treatment. Photographs by ACFV were obtained for registration of the patients’ recovery. Both individuals agreed to have their photographs taken and published.

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Table 4.

Affected organs in acute juvenile PCM cases from this study.

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Fig 3.

Therapeutic regimen prescribed for the treatment of 29 acute juvenile PCM cases from this study.

AMB (amphotericin B) and SMZ/TMP (sulfamethoxazole/trimethoprim). Others: itraconazole + SMZ/TMP; AMB + SMZ/TMP; and AMB + fluconazole + SMZ/TMP.

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