Fig 1.
Map of Japan.
Fig 2.
Temporal dynamics of dog rabies cases in Osaka and Tokyo Prefectures, and total numbers in Japan between 1897 and 1956, the year of elimination.
Fig 3.
Geographical distributions of dog rabies in Osaka Prefecture in a) 1914, b) 1915, c) 1922 and d) 1923, mapped according to cases detected per km2.
Table 1.
Mixed-effects model results for the relationship between logged dog rabies cases per km2 and logged human population density.
Table 2.
Mixed-effects model results for the relationship between logged dog rabies cases per capita and logged human population density.
Fig 4.
Frequency distributions for: a) the infectious period between rabies onset and death in rabid dogs in days; b) the infectious period between rabies onset and when rabid dogs were killed in days; and c) the serial interval between identified primary and secondary cases in days.
Table 3.
Epidemiological parameters estimated.
Fig 5.
Time series of dog rabies cases, dog-bite injuries, and hydrophobia in Osaka Prefecture.
The numbers of dog bite injuries were not recorded in 1913, between 1918 and 1921, and between 1929 and 1933. There were no recorded human rabies deaths in 1913, between 1916 and 1919, between 1921 and 1922, and after 1928.
Fig 6.
Distributions for human rabies: a) incubation period in days; and b) infectious period in days.
Fig 7.
Age distributions of dog-bite victims and the general population in Japan (1914–1933).
Table 4.
Rabies control measures taken in Osaka Prefecture between 1914 and 1933.
Table 5.
The numbers of dogs vaccinated, stray dogs captured, dog-bite injuries by rabid dogs, and PEP in Osaka Prefecture between 1924 and 1928.