Fig 1.
Flow diagram depicting approach to serological evaluation of convalescent and acute phase sera for IgG antibodies to spotted fever group rickettsiae, including ELISA and IFA for R. rickettsii and IFA for R. parkeri.
Note that the IFA substrate slides used resulted in simultaneous tests for both R. rickettsii and R. typhi; those samples identified with R. typhi IFA antibodies were then included in the R. typhi tally (Fig 2) if not R. typhi ELISA reactive.
Fig 2.
Flow diagram depicting approach to serological evaluation of convalescent and acute phase sera for IgG antibodies to R. typhi, including ELISA and IFA.
Note that the IFA substrate slides used resulted in simultaneous tests for both R. rickettsii and R. typhi; those samples identified with R. rickettsii IFA antibodies were then included in the R. rickettsii tally (Fig 1) if not R. rickettsii ELISA reactive.
Table 1.
Clinical characteristics of febrile patients with confirmed acute rickettsial infection vs. no acute rickettsial infection, Nicaragua.
Table 2.
Epidemiologic characteristics of patients with definitive serologic evidence of rickettsial infection vs. no rickettsial infection, Nicaragua, 2008
Table 3.
Clinical characteristics of febrile patients with acute Q fever vs. no acute Q fever, Nicaragua.
Table 4.
Epidemiologic characteristics of patients with definitive serologic evidence of Q fever vs. no Q fever, Nicaragua