Fig 1.
Study selection procedure.
Table 1.
Selected study characteristics.
Fig 2.
Viral load from blood samples in filovirus patients.
Results are for blood or blood products (serum or plasma) until day 24 of illness. Units are as stated in cited articles. Leftside panels a-c: culture only detection methods. Right-side panels d-f: RT-PCR detection only. Bottom chart value = stated limit of detection ([18,25,26,38], all data in panel d) or implied detection threshold (all other sources). Panel source data: a. 1 patient in [20]; b. many patients in [7]; c. averages from many patients in [14]; d. one patient from each of [32,34,39], two patients in [28], four patients in [19] (including the two patients in [28]), many patients in [24]; e. four patients in [18] who are same four patients as in [19] (part of panel d, also duplicated two patients in [28]); f. one patient from each of [25,26,38], six patients in [45] and many patients in [15].
Fig 3.
Probability of positivity for all samples tested by culture through day 110 post illness onset.
The numbers in parenthesis after each fluid type indicate the number of patients who provided samples for each body fluid. The numbers on the right side are the mean probability for positivity (also shown as a cross mark) with 95% confidence interval in parentheses (shown as lines both sides of the cross).
Fig 4.
Probability of positivity for all samples tested by RT-PCR through day 110 of illness onset.
The numbers in parenthesis after each fluid type indicate the number of patients who provided samples for each body fluid. The numbers on the right side are the mean probability for positivity (also shown as a cross mark) with 95% confidence interval in parentheses (shown as lines both sides of the cross).
Fig 5.
Probability of positivity for all samples tested by RT-PCR days 1–16 of illness onset.
The numbers in parenthesis after each fluid type indicate the number of patients who provided samples for each body fluid. The numbers on the right side are the mean probability for positivity (also shown as a cross mark) with 95% confidence interval in parentheses (shown as lines both sides of the cross).
Fig 6.
Probability of positivity for all samples tested by RT-PCR days 17–110 of illness onset.
The numbers in parenthesis after each fluid type indicate the number of patients who provided samples for each body fluid. The numbers on the right side are the mean probability for positivity (also shown as a cross mark) with 95% confidence interval in parentheses (shown as lines both sides of the cross).