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Table 1.

Clinical response definitions.

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Fig 1.

Pafuramidine (DB289) Phase 3 study CONSORT flowchart.

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Table 2.

Baseline demographics.

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Table 2 Expand

Table 3.

Combined rate of cure and probable cure at 12 months.

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Table 4.

Combined rate of cure and probable cure at 24 months.

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Table 5.

Secondary efficacy variables at months 3, 6, 12, 18, and 24 (per-protocol dataset).

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Table 6.

Treatment-emergent adverse events experienced by ≥5% of patients in either treatment group (treatment period).

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