Fig 1.
Total number of patients enrolled and number of CHIKV and DENV RT-qPCR positive cases by week.
The green line graph indicates the number of patients enrolled per week. Histogram bars indicate the number of individuals confirmed as RT-qPCR positive for CHIKV (blue) or DENV (red) by RT-qPCR. Weeks 41–43 in 2014 are excluded as no patient enrolment was attempted during this period.
Table 1.
Bivariable associations between select characteristics of patients of the APCF of the EWMSC, T&T (Dec 2013 –Nov 2014) and having a confirmed infectionⱡ with CHIKV.
Table 2.
Multivariable associations with having a confirmed infectionⱡ with CHIKV in patients of the APCF of the EWMSC, T&T (Dec 2013 –Nov 2014).
Table 3.
Bivariable associations between symptoms and clinical characteristics of patients of the APCF of the EWMSC, T&T (Dec 2013 –Nov 2014) and having a confirmed infectionⱡ with either DENV or CHIKV.
Table 4.
Positive predictive values (PPVs), negative predictive values (NPVs), sensitivity, specificity and likelihood ratios of clinical features used to distinguish patients of the APCF of the EWMSC, T&T (Dec 2013 –Nov 2014) with DF ⱡ and CHIKF ⱡ from patients with other AUFIs.
Table 5.
Positive predictive values (PPVs), negative predictive values (NPVs), sensitivity, specificity and likelihood ratios of clinical features used to distinguish patients of the APCF of the EWMSC, T&T (Dec 2013 –Nov 2014) with DF ⱡ infection from patients with CHIKFⱡ.
Fig 2.
Maximum clade credibility (MCC) phylogeny based on the complete coding region of 74 CHIKV sequences.
The three major CHIKV genotypes are labelled, as well as the IOL within the ECSA clade. Sequences generated from this study (Genbank accession numbers (KR046227 –KR046234) are labelled in blue. Nodes with clade credibilities (posterior probabilities) ≥ 0.95 are labelled accordingly. The clade credibility for the node supporting the Trinidad and BVI sequences is shown in the insert together with the mean estimated time to most recent common ancestor (tMRCA) in years (with 95% HPD in brackets).