Fig 1.
Geographical representation of study area.
Left panel shows the geographical localization of Mozambique in south east Africa (Mozambique is highlighted in pink) and map of Mozambique. Right panel is the representation of the neighborhood of Mavalane health area covered by the Mavalane health center. Mavalane health area comprises two geographical and well delimited areas, namely, Mavalane “A” (dark blue) and Mavalane “B” (pink) neighborhood.
Fig 2.
Flowchart of recruitment of study participants and sample testing.
Study participants were split into two groups, those who returned to the convalescent visit (left side of the flowchart) and those who were lost at follow-up (right side of the flow chart). The left side of the flow chart demonstrates that out of 400 recruited patients, 209 returned for the follow-up visit and their convalescent samples were initially screened for anti-CHIKV IgG. Out of 208 tested samples, 55 (26.4%) were positive and 153 (75.6%) were negative. Further, the corresponding 55 acute samples of the positive samples were screened for anti-CHIKV IgG. A total of 44 (21.2%) were positive with stationary titers, 3 (1.4%) were positive with four fold titer rise and 6 (2.9%) seroconverted. The right side of the flow chart demonstrates that 191 individuals did not return for their follow-up; 156 acute samples were available for testing and of these 38 (24.4%) and 118 (75.6%) were positive and negative, respectively. * Percentage against the total number of patients who returned to convalescent visit. ** Samples not tested because of insufficient volume
Table 1.
Clinical and demographic characteristics of study participants stratified by CHIKV infection status.