Fig 1.
Results of literature search and evaluation of identified studies according to PRISMA.
The searches identified 225 relevant citations, 28 of which were dengue-related sources fulfilling the inclusion criteria. All references identified in the on-line database searches were assigned a unique identification number. Following the removal of duplicates and articles that did not satisfy the inclusion criteria from review of the titles and abstracts, the full papers of the first selection of references were retrieved either electronically or in paper form. A further selection was made based on review of the full text of the articles. ASTMH, American Society of Tropical Medicine and Hygiene; EMBASE, Excerpta Medica Database; LILACS, Latin American and Caribbean Health Sciences Database; LRG, Literature Review Group; PAHO, Pan American Health Organization; PRISMA, preferred reporting items of systematic literature reviews and meta-analyses; SciELO, Scientific Electronic Library Online (*includes access to LILACS and PAHO databases); VHL, Virtual Health Library. Other† includes unique references identified from other reference sources detailed in the protocol and LRG bibliographies.
Fig 2.
Cases of (A) dengue fever and (B) severe dengue fever in Colombia, 2000–2011 [7].
The epidemiology of dengue disease in Colombia was characterized by fluctuations in the number of DF cases (there was a slight baseline increase over time) with major outbreaks in 2001–2003 and 2010. Widespread dengue disease epidemics were observed during 2001–2003 and 2010. A significant outbreak of dengue disease occurred between 2001 and 2003. The annual number of severe dengue disease was highest in 2010, and lowest in 2011.
Table 1.
Number of reported cases of dengue disease and severe dengue disease by region, 2000–2010.
Fig 3.
Incidence of reported cases of dengue (per 100,000 population) by age group, 2000–2010 [7].
In the early part of the review period, the highest incidence of dengue disease was in in individuals aged 15–44 years [12]. However, the age distribution of the disease changed and from 2004 to 2010 the highest reported incidence was in the <4-year-old and 5–14-year-old age groups.
Table 2.
Serotype distribution in Colombia: national and regional data from 2000 to 2010.