Table 1.
Patient information: Baseline characteristics and serology.
Fig 1.
Three patients with microbiologically confirmed early syphilis were treated with a 2.4 megaunit dose of benzathine penicillin at time zero.
Panels A to C represent DNA clearance for three patients and Panels D to F depict RNA clearance for the same patients. Error bars represent 95% confidence intervals.
Table 2.
Measurement of T. pallidum clearance post-treatment.
Fig 2.
A patient presenting with a DGM positive penile ulcer (primary syphilis) was administered a 2.4 megaunit dose of benzathine penicillin at time zero.
Ulcer samples for T. pallidum DNA and RNA quantification were collected pre-treatment and then four hourly for 56 hours. Panel A. presents DNA (tpp047) decay and Panel B. shows 16S rRNA decay.
Table 3.
Serological follow-up of patients