Figure 1.
Tuberculoid granuloma with cuff of lymphocytes coating aggregate of epithelioid histiocytes and giant cells without necrosis in the center (A, hematoxylin and eosin stain, mag. 10X).
Caseating granuloma with caseating necrosis surrounded by epithelioid histiocytes (B, hematoxylin and eosin stain, mag. 20X). Suppurative granuloma with mixed inflammatory infiltrates and necrotic debris in the center (C, hematoxylin and eosin stain, mag. 20X). Sarcoidal/naked granuloma without cuffing lymphocytes and no necrosis noted in the center (D, hematoxylin and eosin stain, mag. 10X).
Table 1.
Modified Ridley's parasitic index for quantification of amastigote load.
Table 2.
The distribution of Ridley's pattern and modified Ridley's parasitic index among 317 cases with Cutaneous Leishmania.
Figure 2.
Cutaneous leishmaniasis presenting as an erythematous nodule (A) with superficial and deep nodular granulomatous dermatitis (B, hematoxylin and eosin stain, mag. 20X) exhibiting caseating granulomas (C, hematoxylin and eosin stain, mag. 40X) with identifiable amastigotes indicated by the arrow (D, hematoxylin and eosin stain, mag. 400X).
Table 3.
Comparison of clinical and microscopic variables between tuberculoid and necrotizing granulomas cases with geographic location and Ridley's pattern being the only 2 variables showing significant difference in distribution (ρ<0.0001).