Table 1.
Summary information on study samples.
Figure 1.
Western blots showing lysate and slurry antigen preparations for each EBOV species.
HMAF poly-clonal antibodies against ZEBOV, SEBOV, REBOV, and CIEBOV (A) and rabbit poly-clonal antibodies against ZEBOV, SEBOV, and REBOV (B), were used as detector antibodies.
Figure 2.
IgM adjusted sum OD values for outbreak samples to each of the five EBOV antigens.
Panels represent samples from Kikwit (A), Gulu (B), and Bundibugyo (C). Closed circles correspond to the adjusted sum OD value for an individual sample to the specific EBOV antigen. Dotted lines are provided to notate the value of an individual sample across all antigens. Footnote: *Adjusted sum OD value is significantly higher to heterologous antigen than to autologous antigen.
Figure 3.
IgG adjusted sum OD values for outbreak samples to each of the five EBOV antigens.
Panels represent samples from Kikwit (A), Gulu (B), Bundibugyo (C), and Philippines (D). Closed circles correspond to the adjusted sum OD value for an individual sample to the specific EBOV antigen. Dotted lines are provided to notate the value of an individual sample across all antigens. Footnote: *Adjusted sum OD value is significantly higher to heterologous antigen than to autologous antigen.
Figure 4.
IgM and IgG adjusted sum OD values to autologous antigen by day of sample collection relative to symptom onset.
Panels correspond to IgM (A) and IgG (B) assays.
Table 2.
Sensitivity of IgM ELISA, using heterologous antigen.
Table 3.
Sensitivity of IgG ELISA, using heterologous antigen.