Table 1.
Summary of the clustering performance and bioinformatic analyses performed on the nucleotide sequences encoded in the transcriptome of the adult stage of each Clonorchis sinensis and Opisthorchis viverrini.
Table 2.
Summary of the bioinformatic analyses performed on the amino acid sequences encoded by the transcriptome of the adult stage of Clonorchis sinensis and Opisthorchis viverrini.
Table 3.
Comparative genomic analysis between Clonorchis sinensis, Opisthorchis viverrini, other parasitic trematodes and selected eukaryotic (model) organisms.
Figure 1.
Venn diagram illustrating the overlap in sequence homology among parasitic trematodes.
Predicted proteins with significant sequence similarity (permissive BLASTx search with E-value <1E−05) among parasitic trematodes, Clonorchis sinensis and Opisthorchis viverrini (family Opisthorchiidae), Schistosoma mansoni (Schistosomatidae) and Fasciola hepatica (Fasciolidae).
Table 4.
Comparative genomic analysis between or among Clonorchis sinensis, Opisthorchis viverrini, Fasciola hepatica, Schistosoma mansoni, S. japonicum (blood flukes) and selected mammals.
Table 5.
Summary of the numbers of unique genes predicted to be expressed by the adult stage of each Clonorchis sinensis and Opisthorchis viverrini based on amino acid sequence similarity to model eukaryotic organisms.
Table 6.
Functions predicted for proteins encoded in the transcriptome of the adult stage of each Clonorchis sinensis and Opisthorchis viverrini based on gene ontology (GO).
Table 7.
Summary of biological key pathways predicted from amino acid sequences encoded in the transcriptome of the adult stage of each Clonorchis sinensis and Opisthorchis viverrini based on homology to annotated proteins in the Kyoto Encyclopedia of Genes and Genomes (KEGG) biological pathways database.
Figure 2.
Characterization of the putative excretory/secretory proteins of the adult stage of each Clonorchis sinensis and Opisthorchis viverrini.
Protein families (A) and biological pathways (B) were assigned to proteins based on their homology to annotated proteins in the Kyoto Encyclopedia of Genes and Genomes (KEGG) biological pathways. Within gene ontology (GO) categories, the parental (i.e. level 2) biological processes (C) were assigned to proteins according to InterPro domains with homology to functionally annotated genes. Individual KEGG and GO categories can have multiple mappings.