Disparities in Global Rabies Burden from GBD 2021: Children, older adults, and low-SDI countries at continued risk
Fig 5
Age-period-cohort analysis of global rabies incidence (1990-2021).
(A) Observed incidence trends by age group and birth cohort. (I) Age-specific incidence rates across six calendar periods (1992-2021). (II) Birth cohort-specific incidence rates, stratified by age. (B) APC model-estimated effects and drift. (I) Net drift and local drifts by age. (II) Age effect adjusted for period and cohort. (III) Period effect showing steady decline in rate ratio from 1.32 in 1995 to 0.47 in 2020. (IV) Cohort effect with RR decreasing from 10.4 in the 1897 birth cohort to 0.10 in cohorts born after 2010.