Novel rabies vaccine candidates development based on pseudotyped lentiviral vectors with rabies virus glycoprotein
Fig 5
Evaluation of anti-RABV-G immunogenicity of pseudotyped recombinant lentivirus in mice after one-dose immunization.
A. Detection of immunized serum anti-RABV-G IgM antibody levels in inoculated mice at 3th and 7th day. B. Detection of immunized serum anti-RABV-G IgG antibody levels in inoculated mice at 1st, 2nd and 3rd week. C. Detection of sustained serum anti-RABV-G IgG antibody titers in different groups. D. Detection of immunized serum neutralizing antibody titers in different groups. ***p < 0.001, **p < 0.01, *p < 0.05, #: The antibody titers did not reach detectable levels.