Cytochrome P450 2D6 (CYP2D6) and glucose-6-phosphate dehydrogenase (G6PD) genetic variations in Thai vivax malaria patients: Implications for 8-aminoquinoline radical cure
Fig 2
Biochemical and structural characterization of recombinant G6PD variants.
(A) Far-UV spectra were recorded over a wavelength range of 190 to 260 nm. (B) Susceptibility to trypsin digestion in the presence of various concentrations of NADP+. (C) Stability analysis upon Gdn-HCl treatment in the presence of various concentrations of NADP+. (D) Thermal stability analysis in the presence of various concentrations of NADP+. Error bars represent the mean ± SD of triplicate measurements.