Vivaxin genes encode highly immunogenic, non-variant antigens on the Trypanosoma vivax cell-surface
Fig 6
Localisation of VIVβ8 by immunolabelled transmission electron microscopy.
Parasites (P) and erythrocytes (E) derived from murine infections were labelled with anti-VIVβ8 polyclonal antibodies. VIVβ8 was localised to the whole parasite cell surface (top and bottom left), and to the parasite flagellum (PF). Anti-VIVβ8-coated gold particles are indicated by white arrows. The right-hand image shows the predominant localisation of VIVβ8 to the surface, although intracellular positions are observed. The graph (inset) shows the proportion of labelled cells and a frequency distribution of the proportion of anti-VIVβ8-coated gold particles found adjacent to the parasite cell membrane of labelled cells.