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Onchocerciasis: Target product profiles of in vitro diagnostics to support onchocerciasis elimination mapping and mass drug administration stopping decisions

Table 7

Effect of specificity on the Type II error when treatment decisions are based on the cluster-specific results, assuming 30 clusters are surveyed and 100 children/cluster.

No sensitivity assumptions were made. The critical cutoff was ≥ 3 positive tests in at least 1 village. The calculations were made for a true prevalence of 0%. At least 99.7% specificity is required to have a Type II error of < 10%.

Table 7

doi: https://doi.org/10.1371/journal.pntd.0010682.t007