Onchocerciasis: Target product profiles of in vitro diagnostics to support onchocerciasis elimination mapping and mass drug administration stopping decisions
Table 6
Effect of sensitivity on the Type I error of a 30-cluster survey involving 3000 children, where treatment decisions are based on the average prevalence of the entire survey area.
A specificity of 99.8% was assumed. The critical cutoff was ≥ 19 positive tests. The calculations were made for a true prevalence of 1%. At least 50% sensitivity is required to have a Type I error of < 5%.