Intrageneric cross-reactivity of monospecific rabbit antisera against venoms of the medically most important Bitis spp. and Echis spp. African snakes
Fig 4
Immunochemical cross-reactivity between anti-Bitis spp. sera.
Cross-reactivity between anti-Bitis spp. monospecific antisera and Bitis spp. venoms was determined by A) ELISA and B) Western blot. ELISA results are expressed as percentage, considering as 100% the titer of sera raised against the homologous venom of each species and correspond to the mean ± SD (n = 4). ↓ Heterologous sera with less than 33% content of specific antibodies of the corresponding homologous serum. LAAO: L-amino acid oxidases, SVMP: Zn2+-dependent snake venom metalloproteinases, SVSP: snake venom serine proteinases, CRISP: cysteine-rich secretory proteins, PLA2: phospholipases A2, CTL: C-type lectin-like proteins.