Estimating dengue transmission intensity from serological data: A comparative analysis using mixture and catalytic models
Fig 5
Age-specific seroprevalence estimates for the IgG data from Vietnam (Dataset A1:A6) and from Indonesia (Dataset B).
Mixture model estimates are in orange, catalytic model estimates are in green and blue when applied under the assumption that the FOI is time-constant or time-varying respectively. Shading represents the 95% Confidence Intervals (CI). The grey points show the observed seroprevalence per age group calculated from the binarily classified IgG data (seropositive individuals / tested individuals), with error bars indicating the 95% exact binomial CIs. The seroprevalence data and model estimates are overlayed for the purpose of comparison. However, it is important to note that the mixture model was not fitted to the data (grey points), as the former does not depend on the titre classification. The size of the grey data points represents the number of individuals tested in each age group.