A recombinant monoclonal-based Taenia antigen assay that reflects disease activity in extra-parenchymal neurocysticercosis
Fig 2
TsG10-TsG10*bt assay determination of the assay cutoff.
A) Receiver operating characteristic (ROC) curve of the S/N results testing 90 uninfected control serum/plasma/CSF samples and 56 serum/plasma/CSF samples from patients with known active SANCC and a positive antigen result by a comparator assay (see Materials and Methods). B) Using the Wilson/Brown method, while maximizing sensitivity and specificity, the S/N threshold for positivity was chosen to be >2.29 (line shown) plotted alongside the sample S/N results used for ROC curve construction shown in (A). Also shown are the S/N from serum samples from patients with active E. granulosus infection.