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Pulmonary haemorrhage as the earliest sign of severe leptospirosis in hamster model challenged with Leptospira interrogans strain HP358

Fig 12

Modulation of pro-inflammatory cytokines and enzymes in the kidneys of control (blue line) and infected hamsters (red line).

Total RNA was extracted from kidneys on day 1 p.i. and days 3 to 7 p.i. D1-D7: Day 1 to day 7. DD: dead. *P≤0.05, **P≤0.01, ***P≤0.001. The fold gene expression value can be found in S2 Table.

Fig 12

doi: https://doi.org/10.1371/journal.pntd.0010409.g012