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Pulmonary haemorrhage as the earliest sign of severe leptospirosis in hamster model challenged with Leptospira interrogans strain HP358

Fig 8

Serum level of total bilirubin, direct bilirubin, CK, ALT, AST, creatinine and urea in control (blue line) and infected hamsters (red lines).

The biochemical measurements convey the function state of the liver and kidney. D1-D7: Day 1 to Day 7. *P≤0.05, **P≤0.01, ***P≤0.001.

doi: https://doi.org/10.1371/journal.pntd.0010409.g008