Pulmonary haemorrhage as the earliest sign of severe leptospirosis in hamster model challenged with Leptospira interrogans strain HP358
Fig 4
Histopathological lesions in the liver of infected hamsters.
Congestion occurred as early as day 1 p.i. while infiltration of inflammatory cells, disorganized hepatocyte cords and swelling of hepatocytes occurred on day 4 p.i. onwards. SC: Sinusoid congestion, IC: Infiltration of inflammatory cells, DHC: Disorganized hepatocyte cords, SH: Swollen hepatocytes and H: Haemorrhage. C: Control, D1-D7: Day 1- day 7 and DD: Dead. Magnification: x100, bar: 100 μm.