Characterization of a novel microfilarial antigen for diagnosis of Wuchereria bancrofti infections
Fig 5
Anti-Wb-Bhp-1 IgG4 ELISA dependence on Mf count.
Graphs show the individual OD490 for the anti-Wb-Bhp-1 IgG4 ELISA. Median values are indicated by black bar. Positivity cutoff of 0.2 is indicated by the dotted black line. Data are color coded by country of origin for the sera. PNG: Papua New Guinea. CDI: Côte d’Ivoire. (A) OD490 titers plotted against the log of Mf count. Values are significantly correlated by Spearman, with r = 0.2982, p<0.0001. (B) OD490 titers from individuals with W. bancrofti infection from the specified country of origin stratified by log of Mf count. Median OD490 and overall percent positivity for each column are significantly different by Kruskal-Wallis, with p< 0.0001.