Characterization of a novel microfilarial antigen for diagnosis of Wuchereria bancrofti infections
Fig 4
Anti-Wb-Bhp-1 IgG4 ELISA sensitivity and specificity.
Graphs show the individual OD490 for the anti-Wb-Bhp-1 IgG4 ELISA. Median values are indicated by the black bar. Positivity cutoff of 0.2 is indicated by the dotted black line. PNG: Papua New Guinea. CDI: Côte d’Ivoire. (A) ELISA data for sera from people with the indicated filarial infection, or non-endemic controls (Table 1). Median ELISA data from each filarial infection are statistically different by Kruskal-Wallis test with p< 0.0001. (B) ELISA data from individuals with W. bancrofti infection from the specified country of origin. Median OD490 and overall percent positivity for each country are significantly different by Kruskal-Wallis, with p<0.0001.