A comparative cross-reactivity and paraspecific neutralization study on Hypnale hypnale, Echis carinatus, and Daboia russelii monovalent and therapeutic polyvalent anti-venoms
Table 2
Neutralization of coagulant activity (Plasma re-calcification time, APTT, and PT assays), and thrombin-like activity of H. hypnale venom by anti-venoms: Hhv was independently pre-incubated with various doses (100–2000 μg/ml) of HhAV, EcAV, DrAV, BhAV, and ViAV for 15 min at room temperature.
In all cases, 20 μg/ml of Hhv alone was considered as 100% coagulant activity and thrombin-like activity. The data is presented as Mean ± SEM (n = 4) and analyzed using one-way ANOVA followed by Bonferroni post-tests, ‘**** p <0.0001, *** p <0.001, ** p <0.01, * p <0.05, and ns (not significant) p >0.05. ‘*’ significant compared to the control group (PBS). ‘*’ significant compared to Hhv+ HhAV.