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Smartphone multiplex microcapillary diagnostics using Cygnus: Development and evaluation of rapid serotype-specific NS1 detection with dengue patient samples

Fig 2

Standard curves for Dengue NS1 detection by Cygnus devices, and examples of dengue patient samples.

Serial dilutions of recombinant NS1 of the indicated serotypes was spiked into (A) 4% BSA or (B) plasma and tested with multiplex MCF in Cygnus devices, n = 4, error bars indicate ± SEM. (C) A set of patient plasma samples were tested in batches of 6 or 12, and images of two example batches of 6 patient samples are shown. The dengue serotype determined by RT-PCR, conventional microplate ELISA and Cygnus are indicated underneath each sample.

Fig 2

doi: https://doi.org/10.1371/journal.pntd.0010266.g002