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Vaccine-linked chemotherapy with a low dose of benznidazole plus a bivalent recombinant protein vaccine prevents the development of cardiac fibrosis caused by Trypanosoma cruzi in chronically-infected BALB/c mice

Fig 2

Representative images of Masson´s trichrome stained-cardiac tissue from (A) non-infected, (B) infected untreated, (C) E6020-SE, (D) low BNZ, (E) vaccine alone and (F) low BNZ plus vaccine experimental groups. Five-nine representative photographs were taken from the myocardial region and were acquired at 10X magnification using a microscope adapted with a digital camera. Cell cytoplasm appears in red and collagen fibbers in blue. Black arrows show fibbers of collagen. Scale bar corresponds to 10μm.

Fig 2

doi: https://doi.org/10.1371/journal.pntd.0010258.g002