Drug metabolism and pharmacokinetics of praziquantel: A review of variable drug exposure during schistosomiasis treatment in human hosts and experimental models
Fig 2
Comparison of the percentage WBR in an infected mouse model when dosing racemic PZQ or a single enantiomer.
The data for this graph were extracted from two papers in this review and evaluated to assess the WBR-dose response [49, 50]. The relationship between WBR and drug formulation was found to be significantly different (*P < 0.01, **P < 0.001) for each PZQ dose based on the results of the independent samples Kruskal-Wallis Test. PZQ, praziquantel; WBR, worm burden reduction.