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Selective inhibition of RNA polymerase I transcription as a potential approach to treat African trypanosomiasis

Table 1

Relative toxicity of Pol I inhibitors in T. brucei compared with human breast epithelial or fibroblast cells expressed as IC50 (μM ± SD)^a.

The selectivity index for T. brucei is indicated in brackets.

doi: https://doi.org/10.1371/journal.pntd.0005432.t001