Low Protective Efficacy of the Current Japanese Encephalitis Vaccine against the Emerging Genotype 5 Japanese Encephalitis Virus
Fig 2
Protection against i.p. challenge with different JE virus strains.
Groups of 10 4-week-old mice were immunized with either (A) 10−3 (2510 pfu), 10−4 (251 pfu) or 10−5 (25 pfu) live attenuated vaccine (LAV) or with (B) 1:5, 1:25 or 1:125 dilutions of inactivated purified vaccine (IPV). Then all mice were challenged i.p. with 500 LD50 JEV P3 or XZ0934 strains.