Effects of Argentilactone on the Transcriptional Profile, Cell Wall and Oxidative Stress of Paracoccidioides spp.
Fig 5
Susceptibility of Paracoccidioides brasiliensis yeast cells exposed to argentilactone.
Samples containing 106, 105 and 104 Pbsod-aRNA, Pbhsp90-aRNA (A), Pbccp-aRNA and Pbrbt5-aRNA (B) yeast cells were spotted in solid Fava Netto’s supplemented with argentilactone at the concentrations of 4.5, 9, 18 and 36 μg/mL. Control cells, wild type (WT) and empty vector (EV) were assayed without argentilactone. The plates were incubated for 7 days at 36°C before photo documentation.