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Structural and Functional Characterization of the Enantiomers of the Antischistosomal Drug Oxamniquine

Fig 5

A) Superimposed structures of R- and S-OXA complex structures in yellow and green, respectively. Hydrogen bonding distances are indicated as dashed lines with distances in Å. B) Alternate view of superimposed enantiomer complex structures highlighting the pucker of the piperidine ring. The chiral carbon is marked (*). Note: some structural elements have been removed for clarity.

Fig 5

doi: https://doi.org/10.1371/journal.pntd.0004132.g005