In Vitro and In Vivo High-Throughput Assays for the Testing of Anti-Trypanosoma cruzi Compounds
Figure 5
Fluorescent T. cruzi-tdTomato expressing parasites imaged post-treatment.
Mice (10 per group) were infected in the hind foot pads with 2.5×105 T. cruzi tdTomato trypomastigotes and the images were taken every two days from day 1 to 11 post infection. (A) Images from days 5, 7 and 9 post infection. (B) Quantification of the fluorescent signal from mice in panel A at all imaging points.