Pulmonary Abnormalities in Mice with Paracoccidioidomycosis: A Sequential Study Comparing High Resolution Computed Tomography and Pathologic Findings
Figure 5
Comparison of the main lung lesion patterns accessed by HRCT and histopathology in the experimental model of PCM.
Figures A, C, E, G correspond to HRCT images and B, D, F, H show the corresponding histopathological lesions taking in coronal plane. The upper left symbol in (A) indicates posterior or dorsal (P), anterior or ventral (A), left (L) and right (R) regions. Dotted lines show an approximated position of the tomographic section. (A) Large nodular lesion represented by a peri-bronquial consolidation (arrow) is located at right hilar region and other left small nodules are indicated by arrowhead. (B) Several nodules with varied sizes. Only the larger nodules are easily seen by tomography. (C) Confluent lesion expressed by left central peri-bronchial consolidation (arrow) extended from the hilum to large area of the parenchyma. (D) Consolidated areas of perivascular and justabronchial granulomatous lesions. (E) Pseudotumoral lesion defining a left central pulmonary mass (arrow). (F) Left central pseudotumoral mass obstructing the bronchus. (G) Left lung with accentuated atelectasis (arrow). (H) Lung section corresponding to figure G showing inflammatory periarterial nodules tending to confluence. Scale bar for HRCT images = 1 cm. Scale bar for histopathological images = 2 mm.