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Open Access
Peer-reviewed
Research Article
Hexokinase-3 upregulation and histone H3K18 lactylation mediate murine liver fibrosis induced by Echinococcus multilocularis
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Yurun Miao ,
Contributed equally to this work with: Yurun Miao, Lixian Shan
Roles Data curation, Formal analysis, Investigation, Methodology, Writing – original draft
Affiliations The State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, School of Life Sciences, Inner Mongolia University, Hohhot, China, Department of Medicine, College of Hetao, Bayannur, China
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Lixian Shan ,
Contributed equally to this work with: Yurun Miao, Lixian Shan
Roles Data curation, Formal analysis, Investigation, Methodology, Writing – original draft
Affiliation The State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, School of Life Sciences, Inner Mongolia University, Hohhot, China
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Jing Liu,
Roles Data curation, Methodology
Affiliation The State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, School of Life Sciences, Inner Mongolia University, Hohhot, China
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Wei Cui,
Roles Data curation
Affiliation The State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, School of Life Sciences, Inner Mongolia University, Hohhot, China
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Xiangyang Yang,
Roles Data curation
Affiliation The State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, School of Life Sciences, Inner Mongolia University, Hohhot, China
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Lei Xiu,
Roles Data curation
Affiliation The State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, School of Life Sciences, Inner Mongolia University, Hohhot, China
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Wenbin Yang,
Roles Data curation
Affiliation The State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, School of Life Sciences, Inner Mongolia University, Hohhot, China
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Chunfu Li,
Roles Data curation
Affiliation The State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, School of Life Sciences, Inner Mongolia University, Hohhot, China
⨯ - Wenhui Liu,
- Yan Wang,
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Ting Zhang ,
Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Writing – review & editing
* E-mail: zhangting@nipd.chinacdc.cn (TZ); huw@imu.edu.cn (WH)
Affiliations The State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, School of Life Sciences, Inner Mongolia University, Hohhot, China, National Health Commission Key Laboratory of Echinococcosis Prevention and Control, Tibet Autonomous Region Center for Disease Control and Prevention, Lhasa, Tibet Autonomous Region, China, National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research); National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, NHC Key Laboratory of Parasite and Vector Biology, WHO Collaborating Centre for Tropical Diseases, Shanghai, China
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Wei Hu
Roles Funding acquisition, Project administration, Supervision
* E-mail: zhangting@nipd.chinacdc.cn (TZ); huw@imu.edu.cn (WH)
Affiliations The State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, School of Life Sciences, Inner Mongolia University, Hohhot, China, State Key Laboratory of Genetic Engineering, Ministry of Education Key Laboratory of Contemporary Anthropology, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai, China
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Hexokinase-3 upregulation and histone H3K18 lactylation mediate murine liver fibrosis induced by Echinococcus multilocularis
- Yurun Miao,
- Lixian Shan,
- Jing Liu,
- Wei Cui,
- Xiangyang Yang,
- Lei Xiu,
- Wenbin Yang,
- Chunfu Li,
- Wenhui Liu,
- Yan Wang
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- Published: July 31, 2026
- https://doi.org/10.1371/journal.pntd.0014582