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Open Access
Peer-reviewed
Research Article
Fecal biomarkers to characterize intestinal inflammation among children with medically attended diarrhea across six low-resource settings: Findings from the Enterics for Global Health (EFGH) Shigella surveillance study
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Bri’Anna Horne ,
Roles Formal analysis, Visualization, Writing – original draft
¶‡ These authors share first authorship and joint senior authors on this work.
Affiliation Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, Maryland, United States of America
⨯ -
Brian Otieno Onyando ,
Roles Writing – original draft
¶‡ These authors share first authorship and joint senior authors on this work.
Affiliation Kenya Medical Research Institute, Center for Global Health Research, Kisumu, Kenya
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Henry Badji ,
Roles Formal analysis, Visualization, Writing – original draft
¶‡ These authors share first authorship and joint senior authors on this work.
Affiliation Medical Research Council Unit The Gambia at the London School of Hygiene & Tropical Medicine, Banjul, The Gambia
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Wardah Mujahid ,
Roles Formal analysis, Visualization, Writing – original draft
¶‡ These authors share first authorship and joint senior authors on this work.
Affiliation Department of Pediatrics and Child Health, Aga Khan University, Karachi, Pakistan
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Taufiqur Rahman Bhuiyan ,
Roles Writing – original draft
¶‡ These authors share first authorship and joint senior authors on this work.
Affiliation International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh
⨯ -
Mutsai Bakali ,
Roles Writing – original draft
¶‡ These authors share first authorship and joint senior authors on this work.
Affiliation Malawi-Liverpool-Welcome Trust, Blantyre, Malawi
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Junaid Iqbal,
Roles Writing – review & editing
Affiliation Department of Pediatrics and Child Health, Aga Khan University, Karachi, Pakistan
⨯ - Maribel Paredes Olortegui,
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Patricia Pavlinac,
Roles Funding acquisition, Investigation, Writing – review & editing
Affiliation Department of Global Health, University of Washington, Seattle, Washington, United States of America
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Bubacar E. Ceesay,
Roles Writing – review & editing
Affiliation Medical Research Council Unit The Gambia at the London School of Hygiene & Tropical Medicine, Banjul, The Gambia
⨯ -
Olivia Schultes,
Roles Data curation, Writing – review & editing
Affiliation Department of Global Health, University of Washington, Seattle, Washington, United States of America
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Sharon M. Tennant,
Roles Investigation, Writing – review & editing
Affiliation Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, Maryland, United States of America
⨯ -
Billy Ogwel,
Roles Writing – review & editing
Affiliation Kenya Medical Research Institute, Center for Global Health Research, Kisumu, Kenya
⨯ -
Desiree Witte,
Roles Writing – review & editing
Affiliations Malawi-Liverpool-Welcome Trust, Blantyre, Malawi, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, United Kingdom
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Hannah Atlas,
Roles Data curation, Writing – review & editing
Affiliation Department of Global Health, University of Washington, Seattle, Washington, United States of America
⨯ -
Naveed Ahmed,
Roles Writing – review & editing
Affiliation Department of Pediatrics and Child Health, Aga Khan University, Karachi, Pakistan
⨯ -
John Benjamin Ochieng,
Roles Writing – review & editing
Affiliation Kenya Medical Research Institute, Center for Global Health Research, Kisumu, Kenya
⨯ -
Khandra Sears,
Roles Writing – review & editing
Affiliation Baltimore City Community College, Baltimore, Maryland, United States of America
⨯ -
Sadia Islam,
Roles Writing – review & editing
Affiliation International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh
⨯ -
Queen Saidi,
Roles Writing – review & editing
Affiliation Division of Infectious Diseases and International Health, University of Virginia, Charlottesville, Virginia, United States of America
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Samba Juma Jallow,
Roles Writing – review & editing
Affiliation Medical Research Council Unit The Gambia at the London School of Hygiene & Tropical Medicine, Banjul, The Gambia
⨯ -
Zarfishan Hussain,
Roles Writing – review & editing
Affiliation Department of Pediatrics and Child Health, Aga Khan University, Karachi, Pakistan
⨯ - Paul Garcia Bardales,
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James A. Platts-Mills,
Roles Funding acquisition, Investigation, Writing – review & editing
Affiliation Division of Infectious Diseases and International Health, University of Virginia, Charlottesville, Virginia, United States of America
⨯ -
Richard Omore,
Roles Investigation, Writing – review & editing
Affiliation Kenya Medical Research Institute, Center for Global Health Research, Kisumu, Kenya
⨯ -
Farhana Khanam,
Roles Writing – review & editing
Affiliation International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh
⨯ -
Md. Parvel Mosharraf,
Roles Writing – review & editing
Affiliation International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh
⨯ -
Ousman Secka,
Roles Writing – review & editing
Affiliation Medical Research Council Unit The Gambia at the London School of Hygiene & Tropical Medicine, Banjul, The Gambia
⨯ - Vitumbiko Munthali,
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Margaret N. Kosek,
Roles Investigation, Writing – review & editing
Affiliation Division of Infectious Diseases and International Health, University of Virginia, Charlottesville, Virginia, United States of America
⨯ - Maureen Ndalama,
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Jen Cornick ,
Roles Investigation, Writing – review & editing
¶‡ These authors share first authorship and joint senior authors on this work.
Affiliations Malawi-Liverpool-Welcome Trust, Blantyre, Malawi, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, United Kingdom
⨯ -
Md. Tahir Yousafzai ,
Roles Investigation, Writing – original draft
¶‡ These authors share first authorship and joint senior authors on this work.
Affiliations Department of Pediatrics and Child Health, Aga Khan University, Karachi, Pakistan, School of Population Health, University of New South Wales, Sydney, Australia
⨯ -
Md. Jahangir Hossain ,
Roles Investigation, Writing – review & editing
¶‡ These authors share first authorship and joint senior authors on this work.
Affiliation Medical Research Council Unit The Gambia at the London School of Hygiene & Tropical Medicine, Banjul, The Gambia
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Catherine Sonye ,
Roles Investigation, Writing – original draft
¶‡ These authors share first authorship and joint senior authors on this work.
Affiliation Kenya Medical Research Institute, Center for Global Health Research, Kisumu, Kenya
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Firdausi Qadri ,
Roles Funding acquisition, Investigation, Writing – review & editing
¶‡ These authors share first authorship and joint senior authors on this work.
Affiliation International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh
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Elizabeth T. Rogawski McQuade ,
Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Visualization, Writing – original draft
* E-mail: sb2yb@virginia.edu (SAB); erogaws@emory.edu (ETRM)
¶‡ These authors share first authorship and joint senior authors on this work.
Affiliation Department of Epidemiology, Emory University, Atlanta, Georgia, United States of America
⨯ - [ ... ],
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Stephanie A. Brennhofer
Roles Data curation, Formal analysis, Methodology, Visualization, Writing – original draft
* E-mail: sb2yb@virginia.edu (SAB); erogaws@emory.edu (ETRM)
¶‡ These authors share first authorship and joint senior authors on this work.
Affiliation Division of Infectious Diseases and International Health, University of Virginia, Charlottesville, Virginia, United States of America
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Fecal biomarkers to characterize intestinal inflammation among children with medically attended diarrhea across six low-resource settings: Findings from the Enterics for Global Health (EFGH) Shigella surveillance study
- Bri’Anna Horne,
- Brian Otieno Onyando,
- Henry Badji,
- Wardah Mujahid,
- Taufiqur Rahman Bhuiyan,
- Mutsai Bakali,
- Junaid Iqbal,
- Maribel Paredes Olortegui,
- Patricia Pavlinac,
- Bubacar E. Ceesay
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- Published: September 15, 2026
- https://doi.org/10.1371/journal.pntd.0014320