The typhoid Mary legacy: Genomic epidemiology uncovers contemporary carriage dynamics across two decades of enteric fever surveillance in England and Wales

• Alice M. Nisbet,

  Roles Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Microbes and Food Safety, Quadram Institute Bioscience, Norwich, United Kingdom, School of Medicine, University of East Anglia, Norwich, United Kingdom, Centre for Microbial Interactions, Norwich Research Park, Norwich, United Kingdom

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• Iman Mohamed,

  Roles Investigation, Writing – review & editing

  Affiliation Travel Health and International Health Regulations Team, United Kingdom Health Security Agency, London, United Kingdom

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• Neville Q. Verlander,

  Roles Formal analysis, Methodology, Writing – review & editing

  Affiliation Statistics, Modelling and Economics Department, United Kingdom Health Security Agency, London, United Kingdom

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• David Powell,

  Roles Data curation, Investigation, Writing – review & editing

  Affiliation Gastrointestinal Bacteria Reference Unit, United Kingdom Health Security Agency, London, United Kingdom

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• Emma V. Waters,

  Roles Writing – original draft, Writing – review & editing

  Affiliations Microbes and Food Safety, Quadram Institute Bioscience, Norwich, United Kingdom, Centre for Microbial Interactions, Norwich Research Park, Norwich, United Kingdom

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• Andrew Nelson,

  Roles Writing – review & editing

  Affiliation Gastrointestinal, Emerging and Zoonotic Infections, Public Health Wales, Cardiff, United Kingdom

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• Hilary Kirkbride,

  Roles Writing – review & editing

  Affiliation Travel Health and International Health Regulations Team, United Kingdom Health Security Agency, London, United Kingdom

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• Gemma C. Langridge,

  Roles Funding acquisition, Supervision, Writing – original draft, Writing – review & editing

  Affiliations Microbes and Food Safety, Quadram Institute Bioscience, Norwich, United Kingdom, Centre for Microbial Interactions, Norwich Research Park, Norwich, United Kingdom

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• Marie A. Chattaway

  Roles Conceptualization, Funding acquisition, Methodology, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: marie.chattaway@ukhsa.gov.uk

  Affiliations Gastrointestinal Bacteria Reference Unit, United Kingdom Health Security Agency, London, United Kingdom, Health Protection Research Unit in Gastrointestinal Infection, University of East Anglia, Norwich, United Kingdom, Health Protection Research Unit in Public Health Genomics, University of Birmingham, Birmingham, United Kingdom

  https://orcid.org/0000-0002-5288-9089

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