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Open Access
Peer-reviewed
Research Article
Pandemic-driven immune imprinting accelerates evolution of human coronavirus OC43
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Shuiping Lu ,
Contributed equally to this work with: Shuiping Lu, Qi Shen, Huanru Wang
Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Resources, Validation, Visualization, Writing – original draft, Writing – review & editing
Affiliation School of Public Health, Fudan University, Key Lab of Public Health Safety, Ministry of Education, Shanghai, China
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Qi Shen ,
Contributed equally to this work with: Shuiping Lu, Qi Shen, Huanru Wang
Roles Data curation, Formal analysis, Investigation, Resources, Validation, Writing – original draft, Writing – review & editing
Affiliation Shanghai Jing’an District Center for Disease Control and Prevention (Shanghai Jing’an District Health Supervision Institute), Shanghai, China
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Huanru Wang ,
Contributed equally to this work with: Shuiping Lu, Qi Shen, Huanru Wang
Roles Data curation, Formal analysis, Investigation, Resources, Validation, Writing – original draft, Writing – review & editing
Affiliation Pathogen Testing Center, Shanghai Municipal Center for Disease Control and Prevention (Shanghai Academy of Preventive Medicine), Shanghai, China
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Mingyi Cai,
Roles Conceptualization, Investigation, Project administration, Resources, Supervision, Validation, Writing – review & editing
Affiliation Shanghai Jing’an District Center for Disease Control and Prevention (Shanghai Jing’an District Health Supervision Institute), Shanghai, China
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Jingjing Hu,
Roles Data curation, Methodology, Resources, Writing – review & editing
Affiliations School of Public Health, Fudan University, Key Lab of Public Health Safety, Ministry of Education, Shanghai, China, Shanghai Institute of Infectious Disease and Biosecurity, Fudan University, Shanghai, China
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Yi Li,
Roles Conceptualization, Investigation, Project administration, Resources, Supervision, Writing – review & editing
Affiliation Shanghai Jing’an District Center for Disease Control and Prevention (Shanghai Jing’an District Health Supervision Institute), Shanghai, China
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Yuxi Wang,
Roles Formal analysis, Methodology, Writing – review & editing
Affiliation School of Public Health, Fudan University, Key Lab of Public Health Safety, Ministry of Education, Shanghai, China
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Feng Yuan,
Roles Investigation, Resources, Supervision, Writing – review & editing
Affiliation Shanghai Jing’an District Center for Disease Control and Prevention (Shanghai Jing’an District Health Supervision Institute), Shanghai, China
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Qingyuan Xu,
Roles Investigation, Resources, Validation, Writing – review & editing
Affiliation Shanghai Jing’an District Center for Disease Control and Prevention (Shanghai Jing’an District Health Supervision Institute), Shanghai, China
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Weijie Chen,
Roles Formal analysis, Methodology, Writing – review & editing
Affiliation School of Public Health, Fudan University, Key Lab of Public Health Safety, Ministry of Education, Shanghai, China
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Yitian Wu,
Roles Investigation, Project administration, Writing – review & editing
Affiliation Shanghai Municipal Center for Disease Control and Prevention, Shanghai, China
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Jiasheng Xiong,
Roles Investigation, Project administration, Writing – review & editing
Affiliation Shanghai Municipal Center for Disease Control and Prevention, Shanghai, China
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Zheng Teng ,
Roles Funding acquisition, Investigation, Project administration, Resources, Supervision, Validation, Writing – review & editing
* E-mail: tengzheng@scdc.sh.cn (ZT); tangmengting@jingancdc.net (MT); xiongchenglong@fudan.edu.cn (CX)
Affiliation Pathogen Testing Center, Shanghai Municipal Center for Disease Control and Prevention (Shanghai Academy of Preventive Medicine), Shanghai, China
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Mengting Tang ,
Roles Investigation, Resources, Validation, Writing – review & editing
* E-mail: tengzheng@scdc.sh.cn (ZT); tangmengting@jingancdc.net (MT); xiongchenglong@fudan.edu.cn (CX)
Affiliation Shanghai Jing’an District Center for Disease Control and Prevention (Shanghai Jing’an District Health Supervision Institute), Shanghai, China
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Chenglong Xiong
Roles Conceptualization, Project administration, Supervision, Writing – review & editing
* E-mail: tengzheng@scdc.sh.cn (ZT); tangmengting@jingancdc.net (MT); xiongchenglong@fudan.edu.cn (CX)
Affiliation School of Public Health, Fudan University, Key Lab of Public Health Safety, Ministry of Education, Shanghai, China
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Pandemic-driven immune imprinting accelerates evolution of human coronavirus OC43
- Shuiping Lu,
- Qi Shen,
- Huanru Wang,
- Mingyi Cai,
- Jingjing Hu,
- Yi Li,
- Yuxi Wang,
- Feng Yuan,
- Qingyuan Xu,
- Weijie Chen
- Published: March 17, 2026
- https://doi.org/10.1371/journal.pntd.0014109