Gut microbiota-associated metabolite N-acetyl-D-glucosamine alleviates systemic inflammatory responses induced by acute Toxoplasma gondii infection

Yang Yang; Chuangchuang Zhou; Chunli Yang; Ziyi Yang; Shan Xu; Xiaoxiao Ma; Shumin Sun; Jing Yang

doi:10.1371/journal.pntd.0014108

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Open Access

Peer-reviewed

Research Article

Gut microbiota-associated metabolite N-acetyl-D-glucosamine alleviates systemic inflammatory responses induced by acute Toxoplasma gondii infection

Yang Yang,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliation College of Veterinary Medicine, Yunnan Agricultural University, Kunming, Yunnan, China
⨯
Chuangchuang Zhou,

Roles Data curation, Formal analysis, Investigation, Methodology, Validation

Affiliation College of Veterinary Medicine, Yunnan Agricultural University, Kunming, Yunnan, China
⨯
Chunli Yang,

Roles Data curation, Formal analysis, Investigation, Methodology, Validation

Affiliation College of Veterinary Medicine, Yunnan Agricultural University, Kunming, Yunnan, China
⨯
Ziyi Yang,

Roles Data curation, Formal analysis, Investigation, Methodology, Validation

Affiliation College of Veterinary Medicine, Yunnan Agricultural University, Kunming, Yunnan, China
⨯
Shan Xu,

Roles Data curation, Formal analysis, Investigation, Methodology, Validation

Affiliation College of Veterinary Medicine, Yunnan Agricultural University, Kunming, Yunnan, China
⨯
Xiaoxiao Ma,

Roles Conceptualization, Resources, Supervision

Affiliation College of Veterinary Medicine, Yunnan Agricultural University, Kunming, Yunnan, China
⨯
Shumin Sun ,

Roles Conceptualization, Project administration, Resources, Supervision

* E-mail: jingyang728@ynau.edu.cn (JY); shums1975@163.com (SS)

Affiliation College of Veterinary Medicine, Yunnan Agricultural University, Kunming, Yunnan, China
⨯
Jing Yang

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Project administration, Resources, Supervision, Visualization, Writing – original draft, Writing – review & editing

* E-mail: jingyang728@ynau.edu.cn (JY); shums1975@163.com (SS)

Affiliation College of Veterinary Medicine, Yunnan Agricultural University, Kunming, Yunnan, China

https://orcid.org/0000-0003-0768-6773

⨯

Gut microbiota-associated metabolite N-acetyl-D-glucosamine alleviates systemic inflammatory responses induced by acute Toxoplasma gondii infection

Yang Yang,
Chuangchuang Zhou,
Chunli Yang,
Ziyi Yang,
Shan Xu,
Xiaoxiao Ma,
Shumin Sun,
Jing Yang

Published: March 13, 2026
https://doi.org/10.1371/journal.pntd.0014108

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