Toxoplasma gondii GRA3 activates interferon-stimulated genes and STAT6 by the cGAS-STING pathway to promote parasite proliferation

• Minmin Wu ,

  Contributed equally to this work with: Minmin Wu, Peihao Wang, Ru Wang

  Roles Formal analysis, Funding acquisition, Investigation, Writing – original draft

  Affiliations Department of Biochemistry and Molecular Biology, Research Center for Infectious Diseases, School of Basic Medical Sciences, Anhui Medical University, Hefei, China, Department of Clinical Laboratory, The First Affiliated Hospital of Anhui Medical University, Hefei, China, Provincial Key Laboratory of Zoonoses of High Institutions in Anhui, Anhui Medical University, Hefei, China

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• Peihao Wang ,

  Contributed equally to this work with: Minmin Wu, Peihao Wang, Ru Wang

  Roles Data curation, Formal analysis, Investigation

  Affiliations Department of Biochemistry and Molecular Biology, Research Center for Infectious Diseases, School of Basic Medical Sciences, Anhui Medical University, Hefei, China, Provincial Key Laboratory of Zoonoses of High Institutions in Anhui, Anhui Medical University, Hefei, China

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• Ru Wang ,

  Contributed equally to this work with: Minmin Wu, Peihao Wang, Ru Wang

  Roles Data curation, Investigation

  Affiliations Department of Biochemistry and Molecular Biology, Research Center for Infectious Diseases, School of Basic Medical Sciences, Anhui Medical University, Hefei, China, Provincial Key Laboratory of Zoonoses of High Institutions in Anhui, Anhui Medical University, Hefei, China

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• Mengting Zhan,

  Roles Formal analysis, Methodology

  Affiliation Department of Anesthesiology, The First Affiliated Hospital of Anhui Medical University, Hefei, China

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• Jie Wang,

  Roles Data curation, Methodology

  Affiliations Department of Biochemistry and Molecular Biology, Research Center for Infectious Diseases, School of Basic Medical Sciences, Anhui Medical University, Hefei, China, Provincial Key Laboratory of Zoonoses of High Institutions in Anhui, Anhui Medical University, Hefei, China

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• Haijian Cai,

  Roles Formal analysis

  Affiliations Department of Biochemistry and Molecular Biology, Research Center for Infectious Diseases, School of Basic Medical Sciences, Anhui Medical University, Hefei, China, Provincial Key Laboratory of Zoonoses of High Institutions in Anhui, Anhui Medical University, Hefei, China

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• Lixia Zha,

  Roles Data curation, Methodology

  Affiliation Department of Anesthesiology, The First Affiliated Hospital of Anhui Medical University, Hefei, China

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• Nan Zhou,

  Roles Resources

  Affiliations Department of Biochemistry and Molecular Biology, Research Center for Infectious Diseases, School of Basic Medical Sciences, Anhui Medical University, Hefei, China, Provincial Key Laboratory of Zoonoses of High Institutions in Anhui, Anhui Medical University, Hefei, China

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• Qingli Luo,

  Roles Formal analysis

  Affiliation Provincial Key Laboratory of Zoonoses of High Institutions in Anhui, Anhui Medical University, Hefei, China

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• Lijian Chen ,

  Roles Conceptualization, Funding acquisition, Supervision, Visualization

  * E-mail: chenlijian77@ahmu.edu.cn (LC); dujian@ahmu.edu.cn (JD)

  Affiliation Department of Anesthesiology, The First Affiliated Hospital of Anhui Medical University, Hefei, China

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• Jian Du

  Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

  * E-mail: chenlijian77@ahmu.edu.cn (LC); dujian@ahmu.edu.cn (JD)

  Affiliations Department of Biochemistry and Molecular Biology, Research Center for Infectious Diseases, School of Basic Medical Sciences, Anhui Medical University, Hefei, China, Provincial Key Laboratory of Zoonoses of High Institutions in Anhui, Anhui Medical University, Hefei, China

  https://orcid.org/0000-0001-5010-7859

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