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Open Access
Peer-reviewed
Research Article
Performance of fecal inflammatory biomarkers to identify watery shigellosis: Findings from the Enterics for Global Health (EFGH) Shigella surveillance study
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Billy Ogwel ,
Roles Conceptualization, Formal analysis, Methodology, Writing – original draft, Writing – review & editing
* E-mail: ogwelbill@gmail.com (OG); elizabeth.rogawski.mcquade@emory.edu (ETRM)
¶☯ These authors are contributed equally to this work as joint first authors.
Affiliation Centre for Global Health Research, Kenya Medical Research Institute, Kisumu, Kenya
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Farhana Khanam ,
Roles Writing – original draft, Writing – review & editing
¶☯ These authors are contributed equally to this work as joint first authors.
Affiliation Infectious Diseases Division, International Centre for Diarrhoeal Disease Research, Bangladesh (icddr, b), Dhaka, Bangladesh
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Henry Badji ,
Roles Writing – original draft, Writing – review & editing
¶☯ These authors are contributed equally to this work as joint first authors.
Affiliation Medical Research Council Unit The Gambia at the London School of Hygiene and Tropical Medicine, Banjul, The Gambia
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Mary Charles ,
Roles Writing – original draft, Writing – review & editing
¶☯ These authors are contributed equally to this work as joint first authors.
Affiliation Malawi Liverpool Wellcome Programme, Blantyre, Malawi
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Sonia Qureshi ,
Roles Writing – original draft, Writing – review & editing
¶☯ These authors are contributed equally to this work as joint first authors.
Affiliation Department of Paediatrics and Child Health, The Aga Khan University, Karachi, Pakistan
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Bri’Anna Horne,
Roles Methodology, Writing – review & editing
Affiliations Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, Maryland, United States of America, Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, United States of America
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Stephanie A. Brennhofer,
Roles Data curation, Methodology, Writing – review & editing
Affiliation Division of Infectious Diseases and International Health, University of Virginia, Charlottesville, Virginia, United States of America
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James A. Platts-Mills,
Roles Investigation, Methodology, Writing – review & editing
Affiliation Division of Infectious Diseases and International Health, University of Virginia, Charlottesville, Virginia, United States of America
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Khandra Sears,
Roles Methodology, Writing – review & editing
Affiliations Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, Maryland, United States of America, Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, United States of America
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Sharon Tennant,
Roles Investigation, Methodology, Writing – review & editing
Affiliations Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, Maryland, United States of America, Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, United States of America
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Sara Kim,
Roles Formal analysis, Writing – review & editing
Affiliation Department of Epidemiology, Emory University, Atlanta, GeorgiaUnited States of America
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Richard Omore,
Roles Investigation, Writing – review & editing
Affiliation Centre for Global Health Research, Kenya Medical Research Institute, Kisumu, Kenya
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Alex O. Awuor,
Roles Methodology, Writing – review & editing
Affiliation Centre for Global Health Research, Kenya Medical Research Institute, Kisumu, Kenya
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Caleb Okonji,
Roles Writing – review & editing
Affiliation Centre for Global Health Research, Kenya Medical Research Institute, Kisumu, Kenya
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Junaid Iqbal,
Roles Writing – review & editing
Affiliation Department of Paediatrics and Child Health, The Aga Khan University, Karachi, Pakistan
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Naveed Ahmed,
Roles Writing – review & editing
Affiliation Department of Paediatrics and Child Health, The Aga Khan University, Karachi, Pakistan
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Zarfishan Hussain,
Roles Writing – review & editing
Affiliation Department of Paediatrics and Child Health, The Aga Khan University, Karachi, Pakistan
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Firdausi Qadri,
Roles Investigation, Writing – review & editing
Affiliation Infectious Diseases Division, International Centre for Diarrhoeal Disease Research, Bangladesh (icddr, b), Dhaka, Bangladesh
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S. M. Azadul Alam Raz,
Roles Writing – review & editing
Affiliation Infectious Diseases Division, International Centre for Diarrhoeal Disease Research, Bangladesh (icddr, b), Dhaka, Bangladesh
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Elias Shawon Bhuiyan,
Roles Writing – review & editing
Affiliation Infectious Diseases Division, International Centre for Diarrhoeal Disease Research, Bangladesh (icddr, b), Dhaka, Bangladesh
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Pablo Penataro Yori,
Roles Writing – review & editing
Affiliation Division of Infectious Diseases and International Health, University of Virginia, Charlottesville, Virginia, United States of America
⨯ - Maribel Paredes Olortegui,
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Margaret N. Kosek,
Roles Investigation, Writing – review & editing
Affiliation Division of Infectious Diseases and International Health, University of Virginia, Charlottesville, Virginia, United States of America
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Samba Juma Jallow,
Roles Writing – review & editing
Affiliation Medical Research Council Unit The Gambia at the London School of Hygiene and Tropical Medicine, Banjul, The Gambia
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Bubacarr E. Ceesay,
Roles Writing – review & editing
Affiliation Medical Research Council Unit The Gambia at the London School of Hygiene and Tropical Medicine, Banjul, The Gambia
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Bakary Conteh,
Roles Writing – review & editing
Affiliation Medical Research Council Unit The Gambia at the London School of Hygiene and Tropical Medicine, Banjul, The Gambia
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Atusaye K. Nyirenda,
Roles Writing – review & editing
Affiliation Malawi Liverpool Wellcome Programme, Blantyre, Malawi
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Vitumbiko Munthali,
Roles Writing – review & editing
Affiliation Malawi Liverpool Wellcome Programme, Blantyre, Malawi
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Clement Lefu,
Roles Writing – review & editing
Affiliation Malawi Liverpool Wellcome Programme, Blantyre, Malawi
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Taufiqur Rahman Bhuiyan ,
Roles Methodology, Writing – review & editing
¶‡ These authros are contributed equally to this work as joint senior authors.
Affiliation Infectious Diseases Division, International Centre for Diarrhoeal Disease Research, Bangladesh (icddr, b), Dhaka, Bangladesh
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Stephen Munga ,
Roles Investigation, Methodology, Writing – review & editing
¶‡ These authros are contributed equally to this work as joint senior authors.
Affiliation Centre for Global Health Research, Kenya Medical Research Institute, Kisumu, Kenya
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M. Jahangir Hossain ,
Roles Investigation, Writing – review & editing
¶‡ These authros are contributed equally to this work as joint senior authors.
Affiliation Medical Research Council Unit The Gambia at the London School of Hygiene and Tropical Medicine, Banjul, The Gambia
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Jennifer Cornick ,
Roles Investigation, Methodology, Writing – review & editing
¶‡ These authros are contributed equally to this work as joint senior authors.
Affiliations Malawi Liverpool Wellcome Programme, Blantyre, Malawi, Department of Clinical Infection, Microbiology and Immunology, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, United Kingdom
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Farah Naz Qamar ,
Roles Investigation, Writing – review & editing
¶‡ These authros are contributed equally to this work as joint senior authors.
Affiliation Department of Paediatrics and Child Health, The Aga Khan University, Karachi, Pakistan
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David Benkeser ,
Roles Formal analysis, Writing – review & editing
¶‡ These authros are contributed equally to this work as joint senior authors.
Affiliation Department of Epidemiology, Emory University, Atlanta, GeorgiaUnited States of America
⨯ - [ ... ],
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Elizabeth T. Rogawski McQuade
Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Writing – original draft, Writing – review & editing
* E-mail: ogwelbill@gmail.com (OG); elizabeth.rogawski.mcquade@emory.edu (ETRM)
¶‡ These authros are contributed equally to this work as joint senior authors.
Affiliation Department of Epidemiology, Emory University, Atlanta, GeorgiaUnited States of America
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Performance of fecal inflammatory biomarkers to identify watery shigellosis: Findings from the Enterics for Global Health (EFGH) Shigella surveillance study
- Billy Ogwel,
- Farhana Khanam,
- Henry Badji,
- Mary Charles,
- Sonia Qureshi,
- Bri’Anna Horne,
- Stephanie A. Brennhofer,
- James A. Platts-Mills,
- Khandra Sears,
- Sharon Tennant
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- Published: June 1, 2026
- https://doi.org/10.1371/journal.pntd.0014025